Frontiers | Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule
Genes | Free Full-Text | Evaluating the Influence of a G-Quadruplex Prone Sequence on the Transactivation Potential by Wild-Type and/or Mutant P53 Family Proteins through a Yeast-Based Functional Assay
Cancers | Free Full-Text | Tipping Growth Inhibition into Apoptosis by Combining Treatment with MDM2 and WIP1 Inhibitors in p53WT Uterine Leiomyosarcoma
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Evolution of p53 Transactivation Specificity through the Lens of a Yeast-Based Functional Assay | PLOS ONE
Interaction between p53 and estradiol pathways in transcriptional responses to chemotherapeutics
Targeting p53 in cancer: from innovative yeast screening strategies to new drugs
Nutlin-Induced Apoptosis Is Specified by a Translation Program Regulated by PCBP2 and DHX30 - ScienceDirect
Cancers | Free Full-Text | Structural and Drug Targeting Insights on Mutant p53
Heatmap of DNA-binding of p53 DBD mutants. Affinity of mutant DBD for... | Download Scientific Diagram
The Biological Impact of the Human Master Regulator p53 Can Be Altered by Mutations That Change the Spectrum and Expression of I
Regulatable expression of p53 protein by using a rheostatable GAL1... | Download Scientific Diagram
Supplementary Materials Evaluating the influence of a G-quadruplex prone sequence on the transactivation potential by wild-type
DIMP53‐1: a novel small‐molecule dual inhibitor of p53–MDM2/X interactions with multifunctional p53‐dependent anticancer properties - Soares - 2017 - Molecular Oncology - Wiley Online Library
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IJMS | Free Full-Text | The Influence of Quadruplex Structure in Proximity to P53 Target Sequences on the Transactivation Potential of P53 Alpha Isoforms
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The Tumor Suppressor Gene TP53: Implications for Cancer Management and Therapy
Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency | bioRxiv
Penka NIKOLOVA | Emeritus Associate Professor | PhD in Biochemistry, 1993 | King's College London, London | KCL | Institute of Pharmaceutical Science | Research profile
Protoporphyrin IX is a dual inhibitor of p53/MDM2 and p53/MDM4 interactions and induces apoptosis in B-cell chronic lymphocytic leukemia cells | Cell Death Discovery
Mutant p53 expression was under the control of the GAL1 promoter while... | Download Scientific Diagram
Genes | Free Full-Text | Evaluating the Influence of a G-Quadruplex Prone Sequence on the Transactivation Potential by Wild-Type and/or Mutant P53 Family Proteins through a Yeast-Based Functional Assay
PDF) Delta N-P63a and TA-P63a exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites
