Combination of dabrafenib plus trametinib for BRAF and MEK inhibitor pretreated patients with advanced BRAFV600-mutant melanoma: an open-label, single arm, dual-centre, phase 2 clinical trial - The Lancet Oncology
Targeted Drug Trio for Colorectal Cancer with BRAF Mutations - NCI
MEK inhibitors for the treatment of non-small cell lung cancer | Journal of Hematology & Oncology | Full Text
Dabrafenib plus Trametinib: Two Kinase Inhibitors Used in Combination to Target Different Parts of the MAPK Pathway | Personalized Medicine in Oncology
Frontiers | Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma
Concurrent MEK2 Mutation and BRAF Amplification Confer Resistance to BRAF and MEK Inhibitors in Melanoma - ScienceDirect
BRAF/MEK Inhibitor Combinations Impressive in Melanoma Trials - The ASCO Post
Frontiers | BRAF-Mutated Non-Small Cell Lung Cancer: Current Treatment Status and Future Perspective
Overcoming Resistance to BRAF and MEK Inhibitors by Simultaneous Suppression of CDK4 | IntechOpen
Mechanistic and Clinical Overview Cardiovascular Toxicity of BRAF and MEK Inhibitors: JACC: CardioOncology State-of-the-Art Review - ScienceDirect
Systemic treatment for BRAF-mutant melanoma: where do we go next? - The Lancet Oncology
BRAF Alterations in Primary Brain Tumors - Stefania Maraka - Discovery Medicine
Mechanistic and Clinical Overview Cardiovascular Toxicity of BRAF and MEK Inhibitors: JACC: CardioOncology State-of-the-Art Review | JACC: CardioOncology
BRAF, MEK and KIT inhibitors for melanoma: adverse events and their management - Livingstone - Chinese Clinical Oncology
Clinical Development of BRAF plus MEK Inhibitor Combinations: Trends in Cancer
Figure 1 from Recent advances in the treatment of melanoma with BRAF and MEK inhibitors. | Semantic Scholar
Tolerability of BRAF/MEK inhibitor combinations: adverse event evaluation and management - ScienceDirect
Cancers | Free Full-Text | Efficacy of BRAF and MEK Inhibition in Patients with BRAF-Mutant Advanced Melanoma and Germline CDKN2A Pathogenic Variants
A combined therapy improves survival in patients with metastatic melanoma | Hospital Clínic Barcelona
Therapeutic potential of combined BRAF/MEK blockade in BRAF-wild type preclinical tumor models | Journal of Experimental & Clinical Cancer Research | Full Text
Biomarkers May Predict Response to BRAF and MEK inhibitors in Malignant Melanoma – OncoPrescribe
Paradoxical oncogenesis—the long-term effects of BRAF inhibition in melanoma | Nature Reviews Clinical Oncology
IJMS | Free Full-Text | Biological Rationale for Targeting MEK/ERK Pathways in Anti-Cancer Therapy and to Potentiate Tumour Responses to Radiation
BRAF/MEK inhibition
Targeting BRAF Mutation Positive Cancers: Melanoma, Lung and Colorectal | Roswell Park Comprehensive Cancer Center - Buffalo, NY
Mechanisms of intrinsic resistance to BRAF-MEK inhibitors. Coexistent... | Download Scientific Diagram
Promising Strategies for Overcoming BRAF Inhibitor Resistance Based on Known Resistance Mechanisms | Bentham Science
The role of BRAF
Mechanisms and strategies to overcome resistance to molecularly targeted therapy for melanoma - Lim - 2017 - Cancer - Wiley Online Library
Management of BRAF-mutant metastatic colorectal cancer: a review of treatment options and evidence-based guidelines - Annals of Oncology