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Combination of dabrafenib plus trametinib for BRAF and MEK inhibitor  pretreated patients with advanced BRAFV600-mutant melanoma: an open-label,  single arm, dual-centre, phase 2 clinical trial - The Lancet Oncology
Combination of dabrafenib plus trametinib for BRAF and MEK inhibitor pretreated patients with advanced BRAFV600-mutant melanoma: an open-label, single arm, dual-centre, phase 2 clinical trial - The Lancet Oncology

Targeted Drug Trio for Colorectal Cancer with BRAF Mutations - NCI
Targeted Drug Trio for Colorectal Cancer with BRAF Mutations - NCI

MEK inhibitors for the treatment of non-small cell lung cancer | Journal of  Hematology & Oncology | Full Text
MEK inhibitors for the treatment of non-small cell lung cancer | Journal of Hematology & Oncology | Full Text

Dabrafenib plus Trametinib: Two Kinase Inhibitors Used in Combination to  Target Different Parts of the MAPK Pathway | Personalized Medicine in  Oncology
Dabrafenib plus Trametinib: Two Kinase Inhibitors Used in Combination to Target Different Parts of the MAPK Pathway | Personalized Medicine in Oncology

Frontiers | Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors:  Implications for Combining Targeted Therapy and Immune Checkpoint Blockade  for the Treatment of Melanoma
Frontiers | Immunomodulatory Effects of BRAF, MEK, and CDK4/6 Inhibitors: Implications for Combining Targeted Therapy and Immune Checkpoint Blockade for the Treatment of Melanoma

Concurrent MEK2 Mutation and BRAF Amplification Confer Resistance to BRAF  and MEK Inhibitors in Melanoma - ScienceDirect
Concurrent MEK2 Mutation and BRAF Amplification Confer Resistance to BRAF and MEK Inhibitors in Melanoma - ScienceDirect

BRAF/MEK Inhibitor Combinations Impressive in Melanoma Trials - The ASCO  Post
BRAF/MEK Inhibitor Combinations Impressive in Melanoma Trials - The ASCO Post

Frontiers | BRAF-Mutated Non-Small Cell Lung Cancer: Current Treatment  Status and Future Perspective
Frontiers | BRAF-Mutated Non-Small Cell Lung Cancer: Current Treatment Status and Future Perspective

Overcoming Resistance to BRAF and MEK Inhibitors by Simultaneous  Suppression of CDK4 | IntechOpen
Overcoming Resistance to BRAF and MEK Inhibitors by Simultaneous Suppression of CDK4 | IntechOpen

Mechanistic and Clinical Overview Cardiovascular Toxicity of BRAF and MEK  Inhibitors: JACC: CardioOncology State-of-the-Art Review - ScienceDirect
Mechanistic and Clinical Overview Cardiovascular Toxicity of BRAF and MEK Inhibitors: JACC: CardioOncology State-of-the-Art Review - ScienceDirect

Systemic treatment for BRAF-mutant melanoma: where do we go next? - The  Lancet Oncology
Systemic treatment for BRAF-mutant melanoma: where do we go next? - The Lancet Oncology

BRAF Alterations in Primary Brain Tumors - Stefania Maraka - Discovery  Medicine
BRAF Alterations in Primary Brain Tumors - Stefania Maraka - Discovery Medicine

Mechanistic and Clinical Overview Cardiovascular Toxicity of BRAF and MEK  Inhibitors: JACC: CardioOncology State-of-the-Art Review | JACC:  CardioOncology
Mechanistic and Clinical Overview Cardiovascular Toxicity of BRAF and MEK Inhibitors: JACC: CardioOncology State-of-the-Art Review | JACC: CardioOncology

BRAF, MEK and KIT inhibitors for melanoma: adverse events and their  management - Livingstone - Chinese Clinical Oncology
BRAF, MEK and KIT inhibitors for melanoma: adverse events and their management - Livingstone - Chinese Clinical Oncology

Clinical Development of BRAF plus MEK Inhibitor Combinations: Trends in  Cancer
Clinical Development of BRAF plus MEK Inhibitor Combinations: Trends in Cancer

Figure 1 from Recent advances in the treatment of melanoma with BRAF and MEK  inhibitors. | Semantic Scholar
Figure 1 from Recent advances in the treatment of melanoma with BRAF and MEK inhibitors. | Semantic Scholar

Tolerability of BRAF/MEK inhibitor combinations: adverse event evaluation  and management - ScienceDirect
Tolerability of BRAF/MEK inhibitor combinations: adverse event evaluation and management - ScienceDirect

Cancers | Free Full-Text | Efficacy of BRAF and MEK Inhibition in Patients  with BRAF-Mutant Advanced Melanoma and Germline CDKN2A Pathogenic Variants
Cancers | Free Full-Text | Efficacy of BRAF and MEK Inhibition in Patients with BRAF-Mutant Advanced Melanoma and Germline CDKN2A Pathogenic Variants

A combined therapy improves survival in patients with metastatic melanoma |  Hospital Clínic Barcelona
A combined therapy improves survival in patients with metastatic melanoma | Hospital Clínic Barcelona

Therapeutic potential of combined BRAF/MEK blockade in BRAF-wild type  preclinical tumor models | Journal of Experimental & Clinical Cancer  Research | Full Text
Therapeutic potential of combined BRAF/MEK blockade in BRAF-wild type preclinical tumor models | Journal of Experimental & Clinical Cancer Research | Full Text

Biomarkers May Predict Response to BRAF and MEK inhibitors in Malignant  Melanoma – OncoPrescribe
Biomarkers May Predict Response to BRAF and MEK inhibitors in Malignant Melanoma – OncoPrescribe

Paradoxical oncogenesis—the long-term effects of BRAF inhibition in  melanoma | Nature Reviews Clinical Oncology
Paradoxical oncogenesis—the long-term effects of BRAF inhibition in melanoma | Nature Reviews Clinical Oncology

IJMS | Free Full-Text | Biological Rationale for Targeting MEK/ERK Pathways  in Anti-Cancer Therapy and to Potentiate Tumour Responses to Radiation
IJMS | Free Full-Text | Biological Rationale for Targeting MEK/ERK Pathways in Anti-Cancer Therapy and to Potentiate Tumour Responses to Radiation

BRAF/MEK inhibition
BRAF/MEK inhibition

Targeting BRAF Mutation Positive Cancers: Melanoma, Lung and Colorectal |  Roswell Park Comprehensive Cancer Center - Buffalo, NY
Targeting BRAF Mutation Positive Cancers: Melanoma, Lung and Colorectal | Roswell Park Comprehensive Cancer Center - Buffalo, NY

Mechanisms of intrinsic resistance to BRAF-MEK inhibitors. Coexistent... |  Download Scientific Diagram
Mechanisms of intrinsic resistance to BRAF-MEK inhibitors. Coexistent... | Download Scientific Diagram

Promising Strategies for Overcoming BRAF Inhibitor Resistance Based on  Known Resistance Mechanisms | Bentham Science
Promising Strategies for Overcoming BRAF Inhibitor Resistance Based on Known Resistance Mechanisms | Bentham Science

The role of BRAF
The role of BRAF

Mechanisms and strategies to overcome resistance to molecularly targeted  therapy for melanoma - Lim - 2017 - Cancer - Wiley Online Library
Mechanisms and strategies to overcome resistance to molecularly targeted therapy for melanoma - Lim - 2017 - Cancer - Wiley Online Library

Management of BRAF-mutant metastatic colorectal cancer: a review of  treatment options and evidence-based guidelines - Annals of Oncology
Management of BRAF-mutant metastatic colorectal cancer: a review of treatment options and evidence-based guidelines - Annals of Oncology